Reverse tolerance with Amanita muscaria is one of the most surprising parts of the journey. Unlike substances that require increasing your dose to feel effects, Amanita often works the opposite way—where the more you work with it, the less you need.
In this post, we’ll explore what reverse tolerance means, how it shows up with muscimol and ibotenic acid, and why tuning into your body matters more than chasing effects.
Reverse Tolerance with Amanita: Why Less Feels Like More Over Time
🍄 Understanding the gentle unraveling of your nervous system
🌿 What is Reverse Tolerance?
Reverse tolerance is a fascinating phenomenon where you need less of a substance over time to feel its effects—the opposite of what happens with most substances.
With Amanita (like muscaria, regalis, and pantherina), many users find that as their body learns to interact with muscimol—the primary active compound—smaller amounts feel deeper, more pronounced, and more energetically aligned.
🔄 Why Does This Happen with Amanita?
The science points to GABA-A receptor modulation. Muscimol acts as a GABA agonist, calming the central nervous system. Over time, your body sensitizes to this calming effect, especially if you’ve lived in a hypervigilant or fight-or-flight state.
But it’s not just chemistry.
It’s also your nervous system finally trusting the stillness.
The more often you enter that state, the more easily your body returns to it.
This is the magic of entrainment—your system learning a new rhythm.
✨ Personal Reflection: “I Didn’t Feel Anything”
The first time I worked with Amanita, I almost dismissed it.
I was expecting fireworks, colors, movement… but what I got was silence.
And at first, that felt like nothing.
But the more I sat with it, the more I realized—that silence was the medicine.
My body, for once, wasn’t bracing. My mind wasn’t spiraling.
And that calm… was so unfamiliar, I didn’t even know it was working.
Weeks later, I needed less. I wanted less.
Because the portal had opened.
My system remembered.
⚠️ Caution: Don’t Chase the Feeling
Reverse tolerance only works if you don’t override it.
If you keep increasing your dose to “feel something,” you may miss the beauty of subtlety.
You’re not supposed to need more. You’re supposed to feel more with less.
Stay with it.
Let the quiet unravel you. Let the medicine whisper.
🔍 Signs It’s Working (Even If You Think It’s Not)
- You feel calmer during moments that used to activate you
- You sleep more deeply
- You respond instead of reacting
- Your thoughts have more space between them
- Your breath slows without you trying
- You feel safe in your own body—maybe for the first time
🌱 Next Steps: Let It Unfold
If you’ve just begun working with Amanita and feel like it’s “not working,” that may be your greatest sign it actually is.
Your job is to stay consistent.
👉 Start small
👉 Stay with the same dose for at least a week
👉 Journal your shifts
👉 Don’t expect a “trip”—expect a return
A return to self.
To stillness.
To your natural rhythm.
🍄 Bonus: Want Support?
Check out our One Month Protocol
You don’t have to walk this path alone.
Book a 1:1 Amanita Consulting Session to:
✔ Understand your body’s unique response
✔ Fine-tune your preparation or dosing
✔ Ask questions you can’t find answers to online
→ Click here to book your session
First-time price: $55 for Tribe Members
Or if you’re just looking to get started:
Grab our ready-made Slurry or 35% decarb Microcapsules—gentle enough for beginners, strong enough for regulars.
Or if you’d rather not DIY your preparation, grab a ready-made Slurry or 35% decarb Microcapsules—gentle enough for beginners, strong enough for regulars.
Stay curious. Stay grounded.
And always—Think Beyond.
🌀 With love,
Marlucia1. What Is Reverse Tolerance?